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Modelling and analysis of protein aggregation - Competing pathways in prion (PrP) polymerisation

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Academic year: 2021

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Figure

Figure 1. SLS experimental data of successive additions of monomers on PrP human fibrils
Figure 3. Simulation of the first three additions of monomers with solute-dilution in the second and third ones.
Table 1. Kinetic constants (k on , k m on , k dep and k m dep ) able to fit the first addition of monomers for the two-compartment model
Figure 5. Quantity of defective fibrils as a function of time for the set of kinetic coeffficients able to fit the heights of the two first additions of monomers (i.e

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