Anion-π Catalysts with Axial Chirality

Anion–π interactions have been introduced to catalysis only recently, and evidence for their significance is so far limited to one classical model reaction in

27 The existence of operational anion- π interactions are supported by increasing activity with (a) increasing π acidity, (b) precise positioning of the reaction on the π surface

Beyond uncertainty: Tied up onto chiral π surfaces in solution, stereoselective proton-deuterium exchange is directly followed by 1 H NMR spectroscopy to see malonate

Anti stereoisomers, with phenyl wings pointing in opposite directions from the central NDI surface, perform best in chloroform/methanol mixtures. With stronger anion–π interactions

Selective deceleration of the favored decarboxylation and selective acceleration of the disfavored addition were both in agreement with the envisioned discrimination of

The relationship between diastereoselectivity and π acidity of stereoisomeric catalysts is more complex (Figure 4A) and, like the profound impact of chiral centers right at the

When in the neutral complex cyano substitu- ents on the NDI are removed, the binding energy increases by 1.9 kJ mol -1 (Figure 6a, entry 1). Remark- ably, upon dicyano NDI

In this report, we demonstrate that anion–p interactions can stabilize the most important anionic reactive intermediates and transition states in chemistry 31,32 and biology