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Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction

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Figure

FIG 1 HIV-1 cell-to-cell transfer from infected T cells to myeloid cells. (A) Experimental protocol
FIG 2 Viral transfer to immature DCs and OCs by cell fusion with infected T cells. (A and C) NLAD8- or NL4.3-infected Jurkat (A, upper images;
FIG 3 Cell fusion between infected T cells and iDCs or OCs by a viral-envelope-dependent mechanism
FIG 4 Virus dissemination between iDCs by homotypic cell fusion. (A and B) NLAD8-infected Jurkat cells were cocultured with iDCs for 6, 24, or 48 h and then stained with phalloidin (actin), anti-Gag, and DAPI (Nuclei) and analyzed by confocal microscopy (A
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