Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5.

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Radioresistant cells expressing TLR5 control the respiratory epithelium’s innate immune responses to flagellin..2. 6 Present address: Glaxosmithkline Biologicals, Rixensart, Belgium

The GM-CSF released by airway epithelial cells orchestrates the mucosal adjuvant activity of flagellin.. Aneesh Vijayan, Laurye van Maele, Delphine Fougeron, Delphine Cayet, Jean

cells that sense bacterial flagellin and stimulates TLR5 signaling. The epithelial cell-driven

Here, we demonstrated that the lung innate immune signature induced by intranasal instillation of flagellin is still effective in a highly inflammatory context with associated

We know from several infectious models that the biological effect of flagellin is at least in part dependent on the administration route (Vijayan et al., 2018): mucosal

Wilson, “Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by toll-like receptor 5,” Infection & Immunity, vol.. Pareja,

Identification of the VvFLS2 grapevine flagellin receptor by a functional genomics strategy..