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Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance

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Academic year: 2021

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Figure 1. Rab4b Expression Is Reduced in CD3 + Lymphocytes from Mice and Human Adipose Tissue in Obesity (A) Rab4b mRNA level in epiWAT of mice (n = 8/group) fed NCD or HFD (45% or 60%) for 16 weeks.
Figure 2. T Cell-Specific Invalidation of the Rab4b Gene in Mice (A) Schematic representation of the strategy.
Figure 3. T Cell-Specific Invalidation of Rab4b Causes Glucose Intolerance and Insulin Resistance with Aging in Chow-Fed Mice and Worsens Insulin Resistance in the Obese State
Figure 4. T Cell-Specific Invalidation of Rab4b Induced Ectopic Lipid Accumulation and an Increase in the Circulating Level of Non-esterified Fatty Acids
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