Prospects for prophylactic hepatitis C vaccines based on virus-like particles.
Texte intégral
Documents relatifs
In our previous work [6] we studied the spread of a viral infection in tissue with a single reaction-diffusion equation for the virus concentration. The concentration of the immune
Hepatitis B and HIV: prevalence, AIDS progression, response to highly active antiretroviral therapy and increased mortality in the EuroSIDA cohort.. All
Wang, Tight junction proteins 10 claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection 11 to prevent superinfection, J Virol, 83
Notably, HepaRG cells support both viral entry and production of cccDNA [36] and are thus suitable for the study of a large number of steps in the HBV life cycle.. In 2007, Schulze
In our study, we were able to clearly demonstrate that native, molecularly intact HCV is capable of establishing infection of both CD4 + and CD8 + T lymphocytes by documenting:
The HCV virion consists of a nucleocapsid comprised of oligomerized core protein and a single copy of the RNA genome, the nucleocapsid is surrounded by a lipid envelope, viral
Cross-neutralizing properties of antibodies induced by immunization with chimeric S+E1-S, S+E2-S or S+E1-S+E2-S particles in the presence of AddaVax ® adjuvant against
These treatments will be given to subjects identified as HCV chronic carriers, but it is estimated that only 5% of infected individuals worldwide are aware of