• Aucun résultat trouvé

THE EXPRESSION OF INOS IN MOUSE EXPERIMENTAL MODEL POINTS TO INFLAMMATORY CONDITIONS ASSOCIATED WITH PARKINSON’S DISEASE

N/A
N/A
Protected

Academic year: 2021

Partager "THE EXPRESSION OF INOS IN MOUSE EXPERIMENTAL MODEL POINTS TO INFLAMMATORY CONDITIONS ASSOCIATED WITH PARKINSON’S DISEASE"

Copied!
1
0
0

Texte intégral

(1)

European Scientific Journal July 2015 edition vol.11, No.21 ISSN: 1857 – 7881 (Print) e - ISSN 1857- 7431

THE EXPRESSION OF INOS IN MOUSE EXPERIMENTAL MODEL

POINTS TO INFLAMMATORY CONDITIONS ASSOCIATED

WITH PARKINSON’S DISEASE

Fatima Laiche Noureddine Djebli

Laboratory of Pharmacognosy & Api Phototherapy-University of Mostaganem; Algeria

Abstract

Parkinson’s Disease (PD) is one of the most common neurodegenerative diseases. Several molecular mechanisms are involved.

The objective of conducting this study was to evaluate the expression of iNOS in mouse experimental model of PD. PD was induced through injecting mice with 10 doses of MPTP (25 mg/kg) and probenecid (250 mg/kg). Mice in control group were injected by saline (25 mg/kg).

Immunohistochemical stains for iNOS in brain sections were carried out using indirect immunoperoxidase techniques. Study findings showed that there was a significant difference in the expression level iNOS in study groups (P<0.001), and experimental PD group had more expressed iNOS levels compared with control group. Taken together, the present study

confirmed the impact of induction of iNOS in the etiology of PD.

Références

Documents relatifs

Studies of the transformation of labor institutions and regulations have focused on what governments have termed &#34;labor reform&#34;, and the outcome has been

As growth continued, the cancer organoid eventually underwent an invasive transition marked by the formation and growth of branches into the ECM; while the core

s =VLs IaeeLgba_JW_Us heG_g]WhhLesWgs HGgLJsa_s'Gghs 'ajeWLes=eG_gMae]s ''=sabLeGhWa_gshVGhsG[[algsGs[alsIa]b[LmWhnsG_JshVGhsGkaWJgs hVLs W_heaJjIhWa_s aMs Gs InI[WIs beLQms Ggs

The bigger the effective key length, the less likely is the attacker to find keys granting the access to the watermarking channel, and therefore, the more secure is the

Compared to other techniques as LIPP (Laser Induced Pressure Pulse) method and TSM (Thermal Step Method), the PEA technique is the only one being not based on the

foil unit, the National Research Council of Canada developed a neutron m.eter em.ploying a scintillation detection unit for use in m.easuring m.oisture in soils from.. a vertical

bassiana and colza oil increased pollen beetle mortality much more than expected from the additive effect of single applications, indicating a strong synergistic effect.. In contrast,

This paper is devoted to the construction and the study of a new algorithm, Fast Marching using Lattice Basis Reduction (FM-LBR), designed to solve the anisotropic eikonal equation