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Association of aminothiols with the clinical outcome in hemodialysis patients: comparison of chromatography and immunoassay for homocysteine determination: aminothiols as predictive factors of hemodialysis outcome

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HAL Id: inserm-00077659

https://www.hal.inserm.fr/inserm-00077659

Submitted on 28 Oct 2008

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Association of aminothiols with the clinical outcome in

hemodialysis patients: comparison of chromatography

and immunoassay for homocysteine determination

Stéphanie Badiou, Isabelle Jaussent, Nathalie Terrier, Estelle Naudin, Hélène

Leray-Moragues, François Maurice, Anne-Marie Dupuy, Jean-Pierre Rivory,

Bernard Canaud, Jean-Paul Cristol, et al.

To cite this version:

Stéphanie Badiou, Isabelle Jaussent, Nathalie Terrier, Estelle Naudin, Hélène Leray-Moragues, et al.. Association of aminothiols with the clinical outcome in hemodialysis patients: comparison of chromatography and immunoassay for homocysteine determination: aminothiols as predictive factors of hemodialysis outcome. Clin Chem Lab Med, 2006, 44 (8), pp.949-54. �10.1515/CCLM.2006.184�. �inserm-00077659�

(2)

Table 2 Relation of homocysteine tertile determined by HPLC with biological parameters (mean

 sem)

.

Levels of significance are corrected using the method of Bonferroni to control for multiple tests. *geometric means. Hcy, µmol/L (p trend) <22.1 [22.1-30.3[ 30.3 Cysteine, µmol/L 373.11  9.01 409.23  13.95 (NS) 464.59  15.33 (<0.0001) Cysteinylglycine *, µmol/L 32.49  1.30 30.92  1.55 (NS) 31.22  1.25 (NS) Hs-CRP*, mg/L 8.20  1.40 7.05  1.13 (NS) 6.31  1.02 (NS) Il6*, pg/mL 13.02 2.36 10.38  1.46 (NS) 10.78  2.07 (NS) Pre creatinine, µmol/L 72929 79631

(NS)

82132 (NS)

Figure

Table 2 Relation of homocysteine tertile determined by HPLC with biological parameters ( mean   sem)

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