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Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes

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Academic year: 2021

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Fig. 1 Principle of the islet-based biosensor: β -cells are cultured on a micro-electrode array (MEA) that records the cells' electrical activity in response to glucose, drugs, and hormones in the incubating solution.
Fig. 2 Proof of principle for implementation of electrophoresis to spatially manipulate cells in micro-electrode arrays (MEAs)
Fig. 3 Influence of applied potential on cell-coverage of electrodes.
Fig. 4 Influence of applied potential on mouse islet cell-coverage of electrodes. (A) Images of mouse islet cells on a micro-electrode array after 10 min exposure to various electric potentials: 0, 1, 1.5, and 2 V (positively charged electrodes indicated b
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