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Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules

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Figure 1 Relative ratio of COL10A1 (A), ALP (B), OPN (C), OC (D) and COL1A1 (E) gene expression in mesenchymal stem cells (MSCs) cultured in osteogenic differentiation medium without (control) or with 0.5 μ M naproxen (Npx)
Figure 3 Effect of naproxen (Npx) on mineral deposition by mesenchymal stem cells (MSCs) cultured in osteogenic differentiation medium.
Figure 4 The relative ratio of IHH (A), PTC1 (B), GLI1 (C), GLI2 (D) and GLI3 (E) expression in mesenchymal stem cells (MSCs) cultured in osteogenic differentiation medium without (control) or with 0.5 μ M naproxen (Npx) for 3, 6, and 12 days
Figure 5 The effect of the Hedgehog (HH) signaling pathway inhibitor cyclopamine (Cpn) on the expression of COL10A1 (A), ALP (B), OPN (C) and COL1A1 (D) in mesenchymal stem cells (MSCs) cultured in osteogenic differentiation medium with 0.5 μ M naproxen (N

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