PTH pre(pmol/L)Ca pre(mmol/L)PTH4h(pmol/)Ca4h(mmol/L)PTH J1(pmol/L)Ca J1(mmol/L)PTH J10(pmol/L) Ca J10(mmol/L)

Table S1 Pre- and post-operative laboratory exams: pre-operative PTH (PTHpre), pre-operative calcium (Ca pre), post-operative 4-hour PTH (PTH4h), post-operative 4-hour calcium (Ca4h), post-operative day 1 (J1), post-operative day 10 (J10)

PTH pre (pmol/L)

Ca pre (mmol/L)

PTH4h (pmol/)

Ca4h (mmol/L)

PTH J1 (pmol/L)

Ca J1 (mmol/L)

PTH J10 (pmol/L)

Ca J10 (mmol/L)

1 8.97 2.53 1.76 2.33 2.58 2.36 4.19 2.39

2 6.57 2.56 1.04 2.34 0.93 2.5 2.78 2.22

3 5.1 2.6 1.39 2.33 1.84 2.29 3.58 2.25

4 19.47 2.83 2.47 2.69 2.27 2.7 5.33 2.53

5 10.5 2.5 0.96 2.62 1.24 2.38 2.26 2.43

6 9.9 2.76 1.53 2.37 1.78 2.39 5.34 2.13

7 17.9 2.55 1.49 2.37 1.55 2.46 2.71 2.31

8 13.1 2.55 1.01 2.48 1.21 2.31 3.65 2.15

9 27.2 2.74 1.91 2.92 1.64 2.68 5.04 2.33

10 9.13 2.62 1.3 2.45 1.54 2.33 4.09 2.42

11 15.77 2.58 1.31 2.35 - - 5.53 2.19

12 31.6 2.87 1.34 2.8 1.13 2.6 2.19 2.47

13 12.9 2.67 2.31 2.51 4.62 2.28 4.04 2.37

14 15.1 2.88 1.35 2.69 1.8 2.67 3.91 2.37

15 15 2.45 1.28 2.34 1.7 2.28 5.15 2.27

16 8.82 2.57 1.21 2.54 1.56 2.38 2.08 2.44

17 9.75 2.62 1.45 2.4 2.12 2.33 2.09 2.38

18 7.8 2.58 1.24 2.48 1.08 2.41 2.24 2.37

19 13.4 2.21 2.36 2.15 2.36 2.17 3.77 2.17

20 10.8 2.75 2.65 2.41 2.3 2.47 3.68 2.37

21 18 2.56 1.97 2.47 3.27 2.39 4.06 2.4

22 16.6 2.71 1.42 2.66 1.06 2.59 3.76 2.25

23 10.5 2.35 1.33 2.22 1.62 2.25 2.57 2.14

Mean 13.65 2.61 1.57 2.47 1.87 2.42 3.65 2.32

SD ± 6.31 ± 0.16 ± 0.48 ± 0.19 ± 0.84 ± 0.15 ± 1.13 ± 0.11

Video S1 NIRAF video captured after the resection of a parathyroid adenoma with Fluobeam LX® device (Fluoptics©, Grenoble, France) showing the marking of the

‘cap’ with the purple surgical marker, of note the ink emits a strong fluorescence

signal