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JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage

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Academic year: 2021

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Fig 1. JMJD6 expression is required for the normal DNA damage response to ionizing radiation exposure
Fig 2. DSB repair using NHEJ is affected by JMJD6 depletion. (A) Relative frequency of Homology-Driven Repair of DSB in JMJD6 depleted cells
Fig 7. JMJD6 expression favours rDNA transcription following DNA damage. (A) Level of rDNA transcription assessed through 5FUrd incorporation following 4 hours of endonuclease-mediated DSBs (AsiSI) in U2OS DIVA cells transfected with the indicated siRNA, i
Fig 8. Nucleolar caps formation in response to DNA damage. (A) Images from endonuclease-induced DSB (4 hours of OHTam treatment) in DIVA cells showing nucleolar caps revealed by UBF foci formation at the nucleolus periphery
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