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Integration of the blaNDM-1 carbapenemase gene into Proteus genomic island 1 (PGI1-PmPEL) in a Proteus mirabilis clinical isolate

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Academic year: 2021

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Supplementary data

Table S1. MICs of β-lactams for NDM-1 and VEB-6 producing P. mirabilis PEL, NDM-1 producing E. coli TOP10 (pPEL-1) and reference strain E. coli TOP10.

MIC (mg/L)a

β-lactam(s) P. mirabilis PEL E. coli TOP10 (pPEL-1) E. coli TOP10

Amoxicillin >256 >256 4 Amoxicillin + CLAb 64 >256 4 Ticarcillin 256 >256 4 Ticarcillin + CLA 32 >256 4 Piperacillin 12 >256 1 Piperacillin + TZB 12 >256 0.5 Ceftazidime >256 >256 0.06 Cefotaxime >256 >256 0.12 Cefepime 64 >256 0.06 Imipenem 32 32 0.12 Meropenem 0.75 >32 0.12 Ertapenem 0.25 >32 0.06 Aztreonam 8 0.09 0.06 a

The MICs were determined by Etest.

b

Figure

Table S1. MICs of β-lactams for NDM-1 and VEB-6 producing P. mirabilis PEL, NDM-1 producing E

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