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Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression.

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Academic year: 2021

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Table 1 Most significantly differentially expressed genes in response to LTC 4 (1 μM) in LPS-primed human coronary artery SMCs (sorted by fold change)
Fig. 2 CysLT 1 receptor expression in human coronary artery smooth muscle cells is upregulated by pro-inflammatory stimuli
Fig. 4 LTC 4 -induced calcium signaling in human coronary artery SMC. a Representative micrographs of Ca 2+

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