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Cell-Intrinsic and cell-extrinsic resistance to classical chemotherapies

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Academic year: 2021

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Figure

Fig. 1. Protocol to create multiple evolutionary replicates of front-line chemotherapy- chemotherapy-resistant cell lines in parallel
Fig. 2 High-throughput drug screen to assess collateral responses to doxorubicin
Fig. 4 Collateral effects of acquiring resistance to (A) doxorubicin, (B) vincristine, (C)  paclitaxel, and (D) cisplatin
Fig. 5 Schematic of a new dimension of tumor heterogeneity. Scientists and physicians  have previously investigated heterogeneity between tumors in different patients,  heterogeneity between different tumors in the same patient, and heterogeneity  within t
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