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Endometrial Tumor Microenvironment Alters Human NK Cell Recruitment, and Resident NK Cell Phenotype and Function

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Academic year: 2021

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FIGURE 1 | NK cell infiltrate is altered in the tumor microenvironment. (A) The number of CD45 + cells recovered per mg of either the tumor or the adjacent tissue (n = 15) was plotted here
FIGURE 2 | Resident NK cells displayed an inhibitory profile in the tumor. (A) Resident NK cells (CD45 + CD3 − CD56 + ) were identified based on CD103 expression
FIGURE 3 | Patient lymph nodes (LN) invasion is associated with higher expression of co-inhibitory molecules in tumor NK cells
FIGURE 5 | NK cells function is altered in the tumor compared to adjacent tissue. Isolated cells from either the tumor or the matching adjacent tissue were cultured overnight at 37 ◦ C

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