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Ebola virus dynamics in mice treated with favipiravir

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Academic year: 2021

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Figure 2: Model of the host-pathogen-drug interactions during infection with EBOV and  treatment with favipiravir
Figure 3: Observed total plasma concentrations (black dots) and median predicted profile (red  line) in mice treated by oral favipiravir 150 mg/kg BID, on the first day of administration (left  panel), and after 14 days of repeated administration (right pa
Table 1: Estimated population parameters of the viral kinetic model. δ is the elimination rate  of infected cells, p is the virion production rate, V 0  is the initial viremia, R 0  is the basic  reproductive number and k e0  is the transfer constant of ef

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