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Toll-like receptor expression and function differ between splenic marginal zone B cell lymphoma and splenic diffuse red pulp B cell lymphoma

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Academic year: 2021

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Figure 1: Pattern of TLR mRNA and protein expressions.  (A) mRNA expression and (B) protein expression of the different TLR  in B cells from non-tumoral, SMZL and SDRPL samples, all from spleen
Figure 2: IL-6 production after TLR7 and TLR9 stimulations. TLR7 and TLR9 stimulations were both assessed with 2  concentrations (2.5 and 5 µg/mL) of agonists
Figure 3: Proliferation and apoptosis upon TLR7 and TLR9 stimulations. Proliferation of B cells in response to TLR  stimulation was assessed by flow cytometry gated on living CFSE low CD19 +  cells
Figure 4: CD86 expression upon TLR7 and TLR9 stimulations.  CD86 expression was assessed by flow cytometry gated on  CD19 +  B cells
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