Modulation of the hepatic fatty acid pool in peroxisomal 3-ketoacyl-CoA thiolase B-null mice exposed to the selective PPARalpha agonist Wy14,643.

These constructs were cotransfected with expression vectors for both mouse PPARα (pSG5- mPPARα) and RXRα (pSG5-mRXRα) together with an expression vector encoding either wild-type

Plasma ammonia levels were normal in nonstressed HLLKO mice (not shown), but elevated in HLLKO mice in crises (263664 mM; KIC-injected normal controls, 63617 mM, n = 5, p,0.05;

Ce travail de recherche contribue à la transition de l'industrie minière vers le développement durable en élaborant un modèle d ' évaluation des impacts socioéconomiques

Moreover, native-PAGE experiments showed that high-molecular weight assemblies for both transporters are present in BV-2 cells and in induced clone 28.38 and are likely to correspond

A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPARα- mediated upregulation of SREBP-2 target genes in the liver.: ThB and cholesterol biosynthesis in

Thus, ACOX1 deficiency in P-NALD fibroblasts leads to the activation of IL-1 inflammatory pathway and enhanced synthesis of its target genes, IL-6 and IL-8 (Fig. CCL26,

Fluorescence microscopy and flow cytometry analysis were accomplished on subconfluent murine oligodendrocytes 158N and JP to determine the expression of

Disturbances in cholesterol, bile acid and glucose metabolism in peroxisomal 3-ketoacylCoA thiolase B deficient mice fed diets containing high or low saturated fat