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Increased Sirt1 secreted from visceral white adipose tissue is associated with improved glucose tolerance in obese Nrf2-deficient mice

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Academic year: 2021

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Figure

Fig.  1. Metabolic  adaptation  of  Nrf2-deficient  mice  fed  a  standard  diet  (SD)  is  associated  with  enhanced  circulating  Sirt1  levels
Fig. 3. Mitochondrial bioenergetics and glucose metabolism in Nrf2-deficient adipocytes
Fig. 4. Improved glucose metabolism, insulin sensitivity and lipid profile in obese Nrf2-deficient mice
Fig. 5. Removal of adipose tissue abolishes the increase in Sirt1 and suppresses the improved glucose metabolism in Nrf2 ¡/¡ obese mice

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