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Prefrontal Markers and Cognitive Performance Are Dissociated during Progressive Dopamine Lesion

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Academic year: 2021

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Figure

Fig 1. Task and BL behaviour. Monkeys perform the PST efficiently prior to MPTP treatment, demonstrating understanding of the task and cognitive control
Fig 2. Frontal neurophysiology in BL. Performance monitoring, cognitive control, and motivation are represented in neurophysiological markers within prefrontal cortex prior to the onset of MPTP treatment
Fig 3. MPTP protocol and behaviour. MPTP lesion induces sub-threshold motor symptoms in the home- home-cage, showing that the lesion is occurring, but motor parameters on the task are not slowed
Fig 4. FRPs in MPTP period. MPTP full dose diminishes the capacity of FRPs to distinguish feedback
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