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Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function.

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Academic year: 2021

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Figure

Figure 2. Effect of protease inhibitors on LRP-1 ectodomain shedding. Western blotting of LRP-1 ␣-chain in media  condi-tioned for 24 h by fibroblastoid HT1080 cells
Figure 4. Shedding of LRP-1 ectodomain is decreased in epithelioid HT1080 cell variant
Figure 6. Cellular cholesterol levels regulate metalloproteinase-dependent shedding of LRP-1 ectodomain
Figure 7. The two HT1080 cell variants show similar distribution of LRP-1, MT1-MMP, and ADAM-12 in Triton X-100 solubility-based  frac-tions

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