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Asthma-related inflammation promotes lung metastasis of breast cancer cells through CCL11–CCR3 pathway

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Academic year: 2021

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Fig. 1  Inflammation generated by OVA challenge induces tumor cell dissemination to the lung parenchyma (n = 8/group)
Fig. 2  Intratracheal injection of CCL11 recombinant (recCCL11) induces 4T1 tumor cell migration to lung tissue (n = 6/group)
Fig. 3  Measurement of CCR3 on 4T1 cells and neutrophils by flow cytometry. a The dot plot diagrams represent typical apoptotic and necrotic 4T1  cell populations detected by Annexin V-FITC and PI staining
Fig. 4  Measurement of CCR3 antagonist (SB-297006) effects on 4T1 cells migration and proliferation

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