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Bile acids induce apoptosis selectively in androgen-dependent and -independent prostate cancer cells

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Academic year: 2021

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Figure 1 Bile acids inhibit proliferation and induce apoptosis in androgen-dependent LNCaP and -independent PC-3 prostate cancer cells
Figure 2 LCA-induced cell death is a caspase-3-dependent process. Cleavage of caspase-3 protein was assessed by western blot (A) and catalytic activity (B) was measured by cleavage of the fluorogenic substrate Ac-DEVD-AFC in response to a 24 h treatment of
Table 1 Extra/intracellular distribution of LCA and UDCA in LNCaP and PC-3 human prostate cancer cells in culture
Figure 3 LCA activates the extrinsic pathway of apoptosis in androgen-dependent and -independent prostate cancer cells
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