Switch: pilot intervention that
targets motivational deficits
in people with schizophrenia
Thonon, B.
a*, Levaux, M.-N.
b, Larøi, F.
a,c,d*benedicte.thonon@uliege.be
Background
__________________
Methods
____________
9 participants with schizophrenia / schizoaffective
disorder participated in Switch for 6 months. 7 of
them followed Switch for 12 months.
T0
T1
T2
T3
(6m, +- 20 sessions) (12m, +- 30 sessions) 18m
n=14 n=9 n=7
Assessement (T0-T3):
•Brief Negative Symptom Scale (BNSS)
Amotivation subscale•Functional Remission of General Schizophrenia (FROGS)
•Schizophrenia - Quality of Life scale (S-QOL)
Results and Discussion
______________________________
a Psychology and Neuroscience of Cognition Research Unit, Université de Liège, Belgium. b Intercommunale de Soins Spécialisés de Liège, Belgium. c Department of Biological and Medical Psychology, University of Bergen, Norway. d NORMENT – Norwegian Center of Excellence for Mental Disorders Research, University of Oslo, Norway.
References and additional information: benedicte.thonon@uliege.be
= Best predictors (Fervaha et al., 2015)
= Resistant to pharmaceutical treatment
(Chue and Lalonde, 2014)
= Target of only a few interventions
(Lincoln and Pedersen, 2019)
Ø Goal
____________
Difficulties in daily
functioning
Low quality of life
Negative symptoms
Motivational
deficits
People with
schizophrenia
45’ / week 0-6 months 45’ / 2 weeks 6-9 months 45’ / 3-4 weeks 9-12 months-Develop + validate a multifactorial intervention
based on models of motivational deficits in
schizophrenia
(Kring and Barch, 2014; Rector et al., 2005)1,5 2,0 2,5 3,0 3,5 4,0 0 1 2 3
Paired sample t-tests
Comparing T1, T2, T3 to T0
Mean scores
BNSS Amotivation S-QOL FROGS M
*
* p < .10 ** p < .05
**
**
• After 6 months of Switch, significant and important reduction in motivational deficits (d=-0.98, p=.02) and functional outcomes (d-0.90, p=.04).
• After 12 months of Switch, significant and important reduction in motivational deficits (d=-0.90, p=0.05). Moderate improvement on functional outcomes, but statistically non-significant (d=0.42,
p=.30).
• 6 months after the end of Switch, moderate reduction in motivational deficits (d=-0.50, p=.23) and functional outcomes (d=0.66, p=.17), but statistically non-significant.
• Zero effect on reported quality of life. Secondary analyses: improvement on satisfaction regarding family relationships.