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Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S-Transferases

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Academic year: 2021

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Figure

FIGURE 1 | Simplified scheme of APAP metabolism, leading to the formation of NAPQI with subsequent GSH conjugation
TABLE 1 | Overview of studied human GST enzymes a .
TABLE 2 | Coverage of iodo-APAP-cysteine sites in DDA HRMS/MS.
FIGURE 4 | Overlaid high-resolution extracted ion chromatograms (±0.01 u) of detected modified peptide precursors (A)
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