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Rôles de l’autophagie dans l'homéostasie des cellules souches intestinales

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Academic year: 2021

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Figure

Figure 21. Demonstration of Lgr5 +  ISC as the drivers of colorectal adenoma growth using Lgr5-EGFP-ires-
Figure 1. Atg7 deletion leads to the inhibition of autophagy throughout the intestinal epithelium and apoptosis of Lgr5 + ISC
Figure 2. Autophagy-deficient Lgr5 + ISC apoptosis is independent of the Paneth cell niche but dependent on p53
Figure 3. Loss of autophagy disrupts DNA damage repair in Lgr5 + ISC.
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