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The practical challenges of the Biosafety officer : interacting with the user

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(1)The practical challenges of the BSO : interacting with the user. 11 december 2008.

(2) Service Universitaire de Protection et d’Hygiène du Travail. University of Liège. !. ".

(3) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety at U.Lg : who is concerned ? (1) $. %. Botanic institute. -. Research on transgenic plants Research on phytopathogens Molecular biology (GM bacteria & yeasts) Production of bacteria in fermentors or bioreactors Use of bacteria & yeasts to produce recombinant proteins Research on animal, plant or human cells (usually GM). (Bio)Chemical institute. #.

(4) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety at U.Lg : who is concerned ? (2) $. '. Pathology tower. -. Use of GM bacteria & yeasts Use of GM zebrafish Use of GM animal and human cell lines or primary cells Production & use of defective viral vectors (lentiviral, adenoviral) Handling of pathogens (HPV, Plasmodium, VZV, prions…). Pharmacy tower. The Interdisciplinary Group of Applied Genoproteomics comprising a center of excellence in academic research (20 research units – 280 employees) &.

(5) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety at U.Lg : who is concerned ? (3) $ -. (. '. Use of GM bacteria and yeasts Housing, breeding and use of transgenic mice Use of GM cell lines and animal primary cells Food microbiology Identification of viruses or bacteria in animal clinical specimens (Salmonella,. Pasteurella, Poxvirus, …). - Handling of animal pathogens (Mycoplasma, parasites, Herpesvirus, Pestivirus,..).

(6) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety at U.Lg : who is concerned ? (4) $. ' + - Housing, breeding and use of transgenic mice - Experiments with biohazard agents (viral vectors, bacteria, VZV,…). $ +. -. * ,. .. ).

(7) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety - who is concerned ? (5) Outside of Liege city / - Research and identification of pathogens in waters - R & D on mould. 1 2%3 3. 0+.

(8) Service Universitaire de Protection et d’Hygiène du Travail. U.Lg Containment facilities 1 %. 5 56 5# 7. 8 8. #. 8. % ( 3. + +#. '. $ 5#. '. " 4.

(9) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety officers at U.Lg. :; 1/ 2%3 < &. %. -%/ ! =- >. % 2%3 < <. :!2; %;. 4. " ". *. 9.

(10) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety committees at U.Lg 3. $. %. .' $. .(. ' 6 2%3. *. ;. 7 ' '. :. ?. ".

(11) Service Universitaire de Protection et d’Hygiène du Travail. Biosafety supervision at U.Lg !. @ A .. . .B.

(12) Service Universitaire de Protection et d’Hygiène du Travail. BSO : summary of our duties 3 ?. ! , ?. ;. 7.

(13) Service Universitaire de Protection et d’Hygiène du Travail. Interaction with users !%/:%. !%/:%. 2%3. 2%3 #.

(14) Service Universitaire de Protection et d’Hygiène du Travail. Users queries and expectations + ?. ;. 7 5 C. C. C. $ A ? ? D. . ?. C. &.

(15) Service Universitaire de Protection et d’Hygiène du Travail. Users queries and expectations E. ;. ". 7 5?C ? , =. F ;. , 7 ? C. ..

(16) Service Universitaire de Protection et d’Hygiène du Travail. Users queries and expectations * . ;. 7. :A %. ,. A GG7. ,. ". ).

(17) Service Universitaire de Protection et d’Hygiène du Travail. Users queries and expectations + +. .. ?. +$% +. ". G7. ? ". ;. 7 *. ?. A I. H.

(18) Service Universitaire de Protection et d’Hygiène du Travail. Interaction with users !%/:%. !%/:%. 2%3. 2%3 4.

(19) Service Universitaire de Protection et d’Hygiène du Travail. BSO assignments (1) 2 5. # "J " 7. ; % 1. D ? ". 5 5?C ?. J5#. 7. 9.

(20) Service Universitaire de Protection et d’Hygiène du Travail. BSO assignments (2) / 8 8. $ $. ;. ?. 7 D !. 7. C.

(21) Service Universitaire de Protection et d’Hygiène du Travail. BSO assignments (3) 2. ?. ; 7 % A 2 2 ? 7 8 % C ? 8 ' 8 1 1. /. ?. ?. ?.

(22) Service Universitaire de Protection et d’Hygiène du Travail. BSO assignments (4) %. Sources of informations : animal ethical commission inspection of working areas.

(23) Service Universitaire de Protection et d’Hygiène du Travail. Animal ethical commission (1) . K. ? C. $ L. ". #.

(24) Service Universitaire de Protection et d’Hygiène du Travail. Animal ethical commission (2). ;. 7 '. +. C GG?. C. 7 2. C ? ,. " &.

(25) Service Universitaire de Protection et d’Hygiène du Travail. Inspection of working areas (1) +. ? ? C. (. ". 7 C. 7 ? A A. ".

(26) Service Universitaire de Protection et d’Hygiène du Travail. ).

(27) Service Universitaire de Protection et d’Hygiène du Travail. Inspection of working areas (2) 3. 7 ;. ? .B". A ; ? C. *. 7 $ H. A II.

(28) Service Universitaire de Protection et d’Hygiène du Travail. Conclusion '. C. 2%3 M. 3. 7 ;. ? ,. ; ?. ?. ? C. , C ?. 4.

(29) Service Universitaire de Protection et d’Hygiène du Travail. Conclusion. 3 / -/: ? C !. ?. 9.

(30) Service Universitaire de Protection et d’Hygiène du Travail. Thank you for your attention !. #.

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