Synthesis of 1,2-methano-tetrahydrofuran derivatives and 1´,2´-methano-2´,3´-dideoxynucleosides as potential antivirals
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After filtration of the potassium bromide, the filtrate was concentrated under reduced pressure and the residue was purified by flash column chromatography on silica
The solvent was evaporated under reduced pressure and the residue was purified by silica gel column chromatography (eluent: Petroleum Ether/CH 2 Cl 2 8/2 to 5/5) to afford
The organic phase was dried over Na 2 SO 4 , and the solvent was removed under reduced pressure before purification by flash column chromatography on silica
The solvent was removed under reduced pressure and the crude was purified by silica gel chromatography (eluent DCM:Et 3 N 99:1) to isolate a fraction that was purified
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Со времени публикации в 2002 г. предыдущей глобальной стратегии многое изменилось. Все больше стран постепенно приходят к пониманию того вклада,
Pump profiling is performed first by defining a fixed amount of flow (demand) objective values, varying from the minimum demand that can be observed (only continuous flows) up to