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Spectroscopic studies and molecular modeling for understanding the interactions between cholesterol and cyclodextrins

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Academic year: 2021

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Figure 3. 1H NMR spectrum of cholesterol in DMSO and atoms notations
Figure 4.  Partial 1H NMR spectra of the cholesterol-CD complex solution (blue) and of the CD solution in D2O with  assignment of the signals of the CD (red): Dimeb (A), Trimeb (B), Rameb (C), Crysmeb (D)
Table 1. Variation of  1 H NMR chemical shifts (ppm)  of Dimeb or Crysmeb protons in the presence of  cholesterol
Figure 5. Two-dimensional ROESY spectrum of a solution containing CD (50 mM) saturated with cholesterol: Dimeb  (A), Trimeb (B), Rameb (C), Crysmeb (D).
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