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TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment.

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Academic year: 2021

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Figure 3. TRAIL-induced apoptosis signaling pathway via the death receptors DR4 and DR5
Figure 6. Current osteosarcoma and Ewing’s sarcoma local and systemic treatment. Approximately 10-16 weeks of  preadjuvant therapy is given to patients before local control measures (surgery and/or radiation for Ewing’s sarcoma)  in an effort to control mi

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