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HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis

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Academic year: 2021

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Figure

Fig 1. Myeloid cells, particularly Ly6C hi and Ly6C lo/int monocytes, accumulate in the spleen of L
Fig 4. L. donovani amastigotes strongly induce iNOS production in HIF-1 α -deficient BMM
Fig 6. HIF-1 α enhances the inhibitory functions of myeloid cells during chronic VL. Na ï ve CD4 T cells were stimulated with plate bound α CD3 and α CD28 in the presence of rIL-12
Fig 8. CD11c-specific HIF-1 α -knockout mice produce more monocyte’s progenitors and display enhanced output of inflammatory monocytes in the bone marrow
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