Blood pressure in haemodialyzed patients: a study by ambulatory blood pressure monitoring during the interdialytic period

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B L O O D P R E S S U R E IN H A E M O D I A L Y Z E D P A T I E N T S : A S T U D Y B Y A M B U L A T O R Y B L O O D P R E S S U R E M O N I T O R I N G D U R I N G T H E I N T E R D I A L Y T I C P E R I O D .

E. GODON , A . S A I N T ' R E M Y , B . DUBOIS, A . POPOVIC, J. P. G O D O N , G. R O R I V E Nephrology-Hypertension Unit. University Hospital. Liège.Belgium

Abstract.The aim of this study is to define wether pre or post dialysis blood pressure (BP) predicted better the usual interdialytic BP, to analyze the influence of haemodialysis on the day-night B P rythm, and finally to evaluate the efifect of interdialytic weight gain on predialysis BP. Therefore B P was measured during the whole interdialytic period using a non invasive ambulatory B P recorder ( S P A C E L A B S 90207) in 10 normotensive (NT) untreated and in 10 hypertensive (HT) treated or untreatd dialyzed patients.

The NT patients présent a day-night rythm although somewhat decreased.On the opposite in HT, BP is higher during the night time. In the sample, B P did not diflfer significantly between day 1 and day 2 of the interdialytic period. But during the dialysis session itself, B P decreases in NT, and increases in HT. The systolic B P load is higher (p<0.04) in the H T compared to the NT. In NT, as well as in HT or in the sample as a whole, a positive significant corrélation is observed between weight gain during interdialy+ic period and the predialysis diastolic B P (NT: p<0.02, HT: p<0.05, the sample as a whole: p< ).01). A multivariate régression analysis indicates that postdialytic B P is significantly related to the interdialytic B P (p< ????)

In conclusion: the post dialysis B P appears to represent better the average interdialytic B P . The efifect of haemodialysis on B P rhythm difife s in N T or in H T patients.