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Determination of the optimal timing for postprandial glucose measurement in pregnant women with gestational diabetes evaluated by the Continuous Glucose Monitoring System IPro®

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Determination of the optimal timing for postprandial glucose measurement in pregnant women with gestational diabetes evaluated by

the Continuous Glucose Monitoring System IPro®

Radermecker RP.*;Philips J.C.;Franck M

Diabetes, Nutrition and Metabolic disorders CHU Liege Belgium, University of Liege

Background and aims

Results

Materials and Methods

Conclusions

Using the Continuous Glucose

Monitoring System (IPro®; Medtronic Minimed) for a group of

pregnant women with gestational diabetes (GD) based on IADSPG criteria (fasting, 5.0 mmol/L; 1-h, 10.0 mmol/L; 2-h, 8.6 mmol/L).We

attempted to answer the following question: when does the physiological peak of postprandial

glucose occur in real life for the 3 meals and after a standardized

breakfast.

We included 13 pregnant women in our study (31 ± 3 years old, 6/13 primipara and 2/13 with GD history).

Patients received an IPro

®CGMS[1] for use over 5 days after an educational program and dietary advises. This was calibrated at least

4 times a day. No problem of intolerance occurred during this trial.

The last day of the trial, patients received a standardized breakfast at

hospital.

The postprandial glucose peak was reached after 68 ± 23 min, 79 ± 30

min and 109 ± 28 for breakfast, lunch and dinner respectively. The

postprandial glucose peak was observed earlier with a standardized

breakfast (70 gr carbohydrates): 52 ± 11 min.

Our results show that the optimal time for testing in pregnant women with GD is between 45 and 120 min

postprandial. Based on a practical approach, it seems to be easier to advise a 60-min interval. In real life, results depend on the type of meals but the earliest peak remains always

at breakfast which could be more discriminant.

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