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Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis

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Academic year: 2021

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Figure

Fig 1. Panx1 is dynamically regulated in the mammary gland and ablated in Panx1 -/- mice
Fig 2. Virgin Panx1 -/- mice have normal mammary glands. (A) Evaluation of body weights at 4 and 7 weeks revealed that pre-pubertal Panx1 -/- mice were significantly larger at 4 weeks compared to control mice
Fig 3. Panx1 -/- mice have normal mammary glands at parturition. (A) Evaluation of body weight, mammary gland weight and normalized mammary gland weight revealed that Panx1 -/- mice were similar to control mice at parturition
Fig 4. Panx1 -/- mice present with a reduction in the number of alveoli during early lactation
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