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Highly Cytotoxic Copper(II) Terpyridine Complexes as Anticancer Drug Candidates

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Academic year: 2021

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Figure 1. Chemical structures of the terminally-functionalised complexes of the type [Cu(2,2´:6´,2´´-terpyridine)(Cl) 2 ] 1-6 and [Cu(2,2´:6´,2´´-terpyridine) 2 ][NO 3 ] 2 7-12
Figure 2. The molecular structure of 3, 5, 6, 7 and 11. Solvent molecules and hydrogen atoms are excluded for clarity
Table 1. Selected geometrical parameters for 3, 5 and 6.
Table 3. IC 50 values (μM) of the bis-coordinated Cu(II) complexes 7-12 against cancerous human adenocarcinomic alveolar basal epithelial (A549), cisplatin resistant human adenocarcinomic alveolar basal epithelial (A549R) and non-cancerous human liver (

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