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Using a combined oxygen-supply and substrate-feeding strategy to improve 2,3-butanediol production by metabolically engineered Klebsiella oxytoca KMS005

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Academic year: 2021

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Figure

Figure 1. Fermentation pathways in K. oxytoca KMS005 under micro-aerobic conditions. Central metabolism indicating genes deleted in the engineered strain for 2,3-BD production
Table 1. Comparison of the performance of batch fermentation for 2,3-BD production by the strain KMS005 from initial glucose concentration of 140 g L −1 with different aeration strategies
Figure 2. Time course of 2,3 BD production by K. oxytoca KMS005 during batch fermentation with different aeration strategies: one-step aeration with (a) low aeration and (b) high aeration, and two-stage aeration with (c) low aeration and (d) high aeration
Table 2. Comparison of the performance of fed-batch fermentation for 2,3 BD production with different sugar feeding strategies
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