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Generation of high drug loading amorphous solid dispersions by different manufacturing processes

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Academic year: 2021

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Figure 2. Schematic representation of oral administration for API absorption and systemic effects [2]–
Figure 4. Solubility challenges in the oral API development. A) marketed APIs and B) APIs in  development [3]
Figure 5. Schematic representation of the breakdown of the solid-state bonds within a crystal
Figure 9. API profile dissolution based on the aqueous solubility of amorphous and crystalline API  and amorphous solid dispersions
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