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The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction.

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Academic year: 2021

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Figure

Table 1. N-terminal sequences of proDer p 3 zymogens obtained after purification at 4 u C.
Table 2. k cat values of 12.5 nM proDer p 3 zymogens determined with the use of 150 m M IEGR-MCA in 50 M polybuffer 1 at 37 u C.
Figure 3. Inter-molecular activation of proDer p 3 zymogens by Der p 1. A: proDer p 3, B: P5A mutant and C: P8A mutant
Table 4. Pseudo first order rate constants (k obs ) for the maturation of the different proDer p 3 zymogens by 11 nM Der p 1
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