Tremblante caprine : évaluation des performances des outils diagnostiques et caractérisation de l'influence des polymorphismes du gène PRP sur la sensibilité à la maladie

We show that the transmission of atypical BSE-H isolates in transgenic mice expressing homologous bovine prion protein (PrP) led to emergence of a clearly distinct prion with

Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting

The lesion distribution pattern resembled that described previously in experimentally BSE- infected pigs [ 21 ] and cattle [ 12 ]; the thalamus was the most affected area,

(A) Complex rumi- nal microbiota of cattle were incubated with scrapie (strain 263K) infected brain homogenated in McDougall mineral salt bu ffer solution under anaerobic conditions

Detection of PrPBSE and prion infectivity in the ileal Peyer’s patch of young calves as early as 2 months after oral challenge with classical bovine spongiform

Estimations of the titre of infectivity in central nervous system (CNS), certain peripheral nerve ganglia and distal ileum tissue were made according to time post exposure from

Several possible reasons are concisely considered: (1) cross contamination may occur during the inoculation procedure, (2) undetectable levels of C-BSE agent by WB analysis emerge

Protease-resistant prion protein distribution pattern in brains of prion protein humanized transgenic mice inoculated with variant Creutzfeldt-Jakob disease (vCJD) on second